Gene regulation and morphogenesis

Investigating the Role of Mitochondrial Prohibitin Complex in Age-Related Neurodegeneration

Dr. Jesus Fernandez Abascal
Researcher associated to Dra Marta Artal Sanz

Summary
Recent publications

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Recent publications

Graziano B, Wang L, White OR, Kaplan DH, Fernandez-Abascal J, Bianchi L. Glial KCNQ K+ channels control neuronal output by regulating GABA release from glia in C. elegansNeuron. 2024 Mar 8; 112:1-16. DOI: https://doi.org/10.1016/j.neuron.2024.02.013.

Wang L, Graziano B, Encalada N, Fernandez-Abascal J, Kaplan DH, Bianchi L. Glial regulators of ions and solutes required for specific chemosensory functions in Caenorhabditis elegans. iScience. 2022 Dec 1;25(12):105684. DOI: https://doi.org/10.1016/j.isci.2022.105684.

Fernandez-Abascal J*, Artal-Sanz M*. Prohibitins in neurodegeneration and mitochondrial homeostasis. Front Aging. 2022 Nov 3;3:1043300. *Corresponding author. DOI: https://doi.org/10.3389/fragi.2022.1043300.

Fernandez-Abascal J, Wang L, Graziano B, Johnson CK, Bianchi L. Exon-dependent transcriptional adaptation by exon-junction complex proteins Y14/RNP-4 and MAGOH/MAG-1 in Caenorhabditis elegans. PLoS Genet. 2022 Oct 31;18(10):e1010488. DOI: https://doi.org/10.1371/journal.pgen.1010488.

Fernandez-Abascal J* and Bianchi L*. A protocol for imaging calcium and chloride in C. elegans glia upon touch stimulation. STAR Protocols. 2022 Jun 17;3(2):101282. *Corresponding author. DOI: https://doi.org/10.1016/j.xpro.2022.101282.

Fernandez-Abascal J, Johnson CK, Graziano B, Wang L, Encalada N, Bianchi L. A glial ClC Cl- channel mediates nose touch responses in C. elegans. Neuron. 2022 Feb 2;110(3):470-485.e7. DOI: https://doi.org/10.1016/j.neuron.2021.11.010.

Fernandez-Abascal J, Graziano B, Encalada N, Bianchi L. Glial chloride channels in the function of the nervous system across species. Ion channels in Biophysics and Physiology. Springer Nature. ISBN: 978-981-16-4253-1. 2021 Nov. DOI: https://doi.org/10.1007/978-981-16-4254-8.
 

Fernandez-Abascal J*, Chiaino E, Frosini M, Davey GP, Valoti M. β-naphthoflavone and ethanol reverse mitochondrial dysfunction in a parkinsonian model of neurodegeneration. International Journal of Molecular Sciences. Multidisciplinary Digital Publishing Institute (MDPI). 2020 May 31;21(11):3955. *Corresponding author DOI: https://doi.org/10.3390/ijms21113955.


Johnson CK*, Fernandez-Abascal J**, Wang Y, Wang L, Bianchi L. The Na+-K+-ATPase is needed in glia of touch receptors for responses to touch in C. elegans. J Neurophysiol. 2020 May 1;123(5):2064-2074. **Equal contribution. DOI: https://doi.org/10.1152/jn.00636.2019.

Fernandez-Abascal J*, Ripullone M, Valeri A, Leone C, Valoti M. β-Naphtoflavone and Ethanol Induce Cytochrome P450 and Protect Towards MPP⁺ Toxicity in Human Neuroblastoma SH-SY5Y Cells. International Journal of Molecular Sciences. Multidisciplinary Digital Publishing Institute (MDPI). 2018 Oct 28;19(11):3369. *Corresponding author. DOI: https://doi.org/10.3390/ijms19113369.

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