Cell biology and Biotechnology

Genetic regulation of ageing in Caenorhabditis elegans

Five relevant publications

  • Inhibition of acid sphingomyelinase increases SMN levels and connects sphingolipid metabolism to Spinal Muscular Atrophy. (2025). Brokate-Llanos AM, Beltran M, Garzón A, Garcera A, Miralles MP, Celma-Nos F, Campoy-López A, Soler RM, Muñoz MJ, Pérez-Pulido AJ.  Biomedicine & Pharmacotherapy. 192, November, 118610. doi: 10.1016/j.biopha.2025.118610.
  • Monosaccharides improve symptoms of an animal model for type III galactosemia, through the activation of the insulin pathway. (2024).  Lucas-Rodríguez P, Brokate-Llanos AM, Hernandez-Curiel JM, Murdoch PDS, Garzón A, Carrión A, Muñoz MJ. Biomedicine and Pharmacotherapy  181, December, 117677. doi: 10.1016/j.biopha.2024.117677. 
  • Nematode biomass production from sewage sludge as a novel method for circular economy. (2022). López-Viso C., Hodaifa G., Muñoz M. J. Journal of Cleaner Production 330. DOI: 10.1016/j.jclepro.2021.129706
  • Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases. (2021). Pérez-Jiménez MM, Monje-Moreno JM, Brokate-Llanos AM, Venegas-Calerón M, Sánchez-García A, Sansigre P, Valladares A, Esteban-García S, Suárez-Pereira I, Vitorica J, Ríos JJ, Artal-Sanz M, Carrión ÁM, Muñoz MJ.  Nature communication; 12-49. doi: 10.1038/s41467-020-20269-y.
  • Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity. (2003). Muñoz, M.J., Riddle, D.L. Genetics, 163(1), pp. 171–180. DOI: 10.1093/genetics/163.1.171

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