Cell biology and Biotechnology

Control of nuclear proteostasis

Five relevant publications

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  • Hydroxyurea induces an oxidative stress response that triggers ER expansion and cytoplasmic protein aggregation. Sánchez-Molina A, Bernal M, Posligua-García JD, Pérez-Pulido AJ, de Cubas L, Hidalgo E, Valdivieso MH, Salas-Pino S, Daga RR . PLoS Biol. 2025 Nov 19;23(11):e3003493. doi: 10.1371/journal.pbio.3003493
  • Limiting 20S proteasome assembly leads to unbalanced nucleo-cytoplasmic distribution of 26S/30S proteasomes and chronic proteotoxicity. Ruiz-Romero G, Berdún MD, Hochstrasser M, Salas-Pino S, Daga RR. iScience. 2024 Oct 4;27(11):111095. doi: 10.1016/j.isci.2024.111095
  •  Acute Heat Stress Leads to Reversible Aggregation of Nuclear Proteins into Nucleolar Rings in Fission Yeast. Gallardo P, Real-Calderón P, Flor-Parra I, Salas-Pino S, Daga RR. Cell Rep. 2020 Nov 10;33(6):108377. doi: 10.1016/j.celrep.2020.108377
  • Selective Nuclear Pore Complex Removal Drives Nuclear Envelope Division in Fission Yeast. Expósito-Serrano M, Sánchez-Molina A, Gallardo P, Salas-Pino S*, Daga RR. Curr Biol. 2020 Aug 17;30(16):3212-3222.e2. doi: 10.1016/j.cub.2020.05.066
  • The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components. Salas-Pino S, Gallardo P, Barrales RR, Braun S, Daga RR. J Cell Biol. 2017 Nov 6;216(11):3591-3608. doi: 10.1083/jcb.201612194

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