Gene regulation and morphogenesis

Relevant publications (2012-2023)

• Letelier J*(CA)#, Buono L*, Almuedo-Castillo M, Zang J, Mounieres C, González-Díaz S, Polvillo R, Sanabria-Reinoso E, Corbacho J, Sousa-Ortega A, Diez del Corral R, Neuhauss SCF, Martínez-Morales JR (CA)#. (2023) Mutation of Vsx genes in zebrafish highlights the robustness of the retinal specification network. Elife May 25;12:e85594. doi: 10.7554/eLife.85594.
• Sousa-Ortega A*, Vázquez-Marín J*, Sanabria-Reinoso E, Corbacho J, Polvillo R, Campoy-López, A, Buono L, Loosli F, Almuedo-Castillo M (CA)#, Martínez-Morales JR (CA)#. (2023). A Yap-dependent mechano-regulatory program sustains cell migration for embryo axis assembly. Nat Comm. May 16th 14(1):2804.1. doi: 10.1038/s41467-023-38482-w.
• Corbacho J, Sanabria-Reinoso E, Buono L, Fernández-Miñan A, Martínez-Morales JR (CA). (2022) Trap-TRAP, a Versatile Tool for Tissue-Specific Translatomics in Zebrafish. Front Cell Dev Biol. May 16th 14(1):2804.1. doi: 10.3389/fcell.2021.817191
• Buono L, Corbacho J, Naranjo S, Almuedo-Castillo M, Moreno-Marmol T, de la Cerda B, Sanabria-Reinoso E, Polvillo R, Díaz-Corrales FJ, Bogdanovic O, Bovolenta P, Martínez-Morales JR. (2021) Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish. Nat Comm. Jul 27;12(1):4665.
  doi: 10.1038/s41467-021-24834-x.
• Vázquez-Marín J, Gutiérrez-Triana JA, Almuedo-Castillo M, Buono L, Gómez-Skarmeta JL, Mateo JL, Wittbrodt J, Martínez-Morales JR. (2019). yap1b, a divergent Yap/Taz family member, cooperates with yap1 in survival and morphogenesis via common transcriptional targets. Development. Jun 21;146(13):dev173286.
  doi: 10.1242/dev.173286.
• Letelier J#, de la Calle-Mustienes E#, Pieretti J, Naranjo S, Maeso I, Nakamura T, Pascual-Anaya J, Shubin NH*, Schneider I*, Martinez-Morales JR*, Gómez-Skarmeta JL*. (2018)  A conserved Shh cis-regulatory module highlights a common developmental origin of unpaired and paired fins. Nature Genetics 50(4):504-509.
  doi: 10.1038/s41588-018-0080-5.
• Letelier J#, Terriente J#, Belzunce I, Voltes A, Undurraga CA, Polvillo R, Devos L, Tena JJ, Maeso I, Retaux S, Gomez-Skarmeta JL, Martínez-Morales JR*, Pujades C* (2018) Evolutionary emergence of the rac3b/rfng/sgca regulatory cluster refined mechanisms for hindbrain boundaries formation. PNAS 115(16):E3731-E3740.
  doi: 10.1073/pnas.1719885115.
• Nicolás-Pérez M, Kuchling F, Letelier J, Polvillo R, Wittbrodt J, Martínez-Morales JR.(2016) Analysis of cellular behavior and cytoskeletal dynamics reveal a constriction mechanism driving optic cup morphogenesis. eLife. 2016 Oct 31;5. pii: e15797.
  doi: 10.7554/eLife.1
• Gago-Rodrigues I, Fernández-Miñán A, Letelier J, Naranjo S, Tena JJ, Gómez-Skarmeta JL, Martinez-Morales JR (2015) Analysis of opo cis-regulatory landscape uncovers Vsx2 requirement in early eye morphogenesis. Nat Comm  6:7054.
  doi: 10.1038/ncomms8054.
• Tena JJ#, González-Aguilera C#, Fernández-Miñán A, Vázquez-Marín J, Parra-Acero H, Cross JW, Rigby PW, Carvajal JJ, Wittbrodt J, Gómez-Skarmeta JL*, Martínez-Morales JR* (2014) Comparative epigenomics in distantly related teleost species identifies conserved cis-regulatory nodes active during the vertebrate phylotypic period. Genome Research. 24(7): 1075-85
• Muller C#, Maeso I#, Wittbrodt J*, Martínez-Morales JR* (2013) The medaka mutation tintachina sheds light on the evolution of V-Atpase B subunits in vertebrates. Scientific Reports 3. 3217
• Bogdanovic O#, Delfino-Machín M#, Nicolás-Pérez M, Gavilán MP, Gago-Rodrigues I, Fernández-Miñán A, Lillo C, Ríos RM, Wittbrodt J, Martínez-Morales JR# (2012) Numb/Numbl-Opo antagonism controls retinal epithelium morphogenesis by regulating integrin endocytosis. Developmental Cell. 23 (4)

*Co-corresponding authors. #equal contribution.

Full list of publications here