Gene regulation and morphogenesis

Cell fate determination in early mammalian development

Five relevant publications

See ORCID / Google Scholar for a complete record

* - equal contribution; † - corresponding author

Zaffagnini G, Cheng S,  Salzer MC, Pernaute B, Duran JM, Irimia M, Schuh M, Böke E† (2024). Mouse oocytes sequester aggregated proteins in degradative super-organelles. Cell. Feb 29;187(5):1109-1126.e21. doi: 10.1016/j.cell.2024.01.031.

Pernaute B
*, Sanchez-Nieto JM*, Pérez-Montero S*, di Gregorio A, Lima A,…, and Rodríguez TA† (2022). DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism. Dev Cell. un 6;57(11):1316-1330.e7

Wyatt CDR*, Pernaute B*†, Gohr A, Miret-Cuesta M,…, and Irimia M† (2022). A developmentally programmed splicing failure contributes to DNA damage response attenuation during mammalian zygotic genome activation. Sci Adv Apr 15;8(15):eabn4935

Spruce T†, Plass M, Gohr A,…, Pernaute B† and Irimia M† (2022). The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians. Plos Biol Apr 27;20(4):e3001615

Pernaute B, Spruce T, Smith KM,..., and Rodriguez TA† (2014). MicroRNAs control the apoptotic threshold in primed pluripotent stem cells through regulation of BIM. Genes & Dev. Sep 1;28(17):1873-8.
 

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