Research Groups

Cell biology and Biotechnology

Dr Plácido Navas Lloret. UPO
Control of oxidative stress
Dr Plácido Navas Lloret. UPO
Principal Investigator

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Five relevant publications

  • Asencio C., Rodríguez-Aguilera J.C., Ruiz-Ferrer M., Vela J. and Navas P. (2003) Silencing of ubiquinone genes extends life span in Caenorhabditis elegans. FASEB J. 17, 1135-1137.
  • Padilla, S., Jonassen, T., Jimenez-Hidalgo, M., Moreno, D.J., Lopez-Lluch, G., Navas, P., Clarke, C.F. and Santos-Ocaña, C. (2004) Demethoxy-Q, an Intermediate of Coenzyme Q Biosynthesis, Fails to Support Respiration in Saccharomyces cerevisiae and Lacks Antioxidant Activity. J. Biol. Chem. 279, 25995-26004
  • Quinzii, C; Naini, A. ; Salviati, L. ; Trevisson, E. ; Navas, P.; DiMauro, S.and Hirano, M. (2006) A mutation in 4-para-hydroxybenzoate:polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency. Am J Human Genetics 78, 345-349.
  • López-Lluch, G., Hunt, N., Jones, B., Zhu, M., Jamieson, H., Hilmer, S.,Cascajo, M.V., Allard, J., Ingram, D.K., Navas, P. De Cabo, R. (2006) Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. Proc. Natl. Acad. Sci. USA 103, 1768-1773.
  • Baur, J.A., Pearson, K. J.,et al. (2006). Resveratrol mimics a low calorie diet and extends lifespan in mice. Nature 444, 337-342.

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