Research Groups

Cell biology and Biotechnology

Dr Ana M. Rojas. CSIC
Bioinformatics and Computational Biology
Dr Ana M. Rojas. CSIC
Principal Investigator

» Summary » Relevant publications (selected) » Lab members & Collaborators » back to research groups

Relevant publications (selected)

  1. Jimenez-Panizo, A; Alegre-Marti,A.; Tettey, T., Fetweiss,G.; Abella-Monleon.M.; Anton, R.; Johnosn, T.; Kim, S.; Lousi, S., Nuñez-Barrios, I.; Font-Diaz, J.; Caelles, C.; Valledor, A.; Perez, P.; Rojas, A.; Fernandez-Rcio, J.; Presman, D.; Hager, D.; Fuentes-Prior, P., Estebanez-Perpiña,E. The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities. 2022. In pressNucleic Acids Research.
  2. Mencucci, MV, Rojas-Mendoza, AM., Andres-Leon,E., Lisi-Roman,C., Gagliardino,JJ, Abba,MC., Maiztegui,B. dentification of novel microRNAs associated with type 2 diabetes by an integrative bioinformatic analysis. 2022. In pressHuman Gene
  3. Verdugo-Sivianes, EM, Rojas, AM, Muñoz-Galván,S., Otero-Albiol, D., Carnero, A. 2020. Mutation of SPINOPHILIN (PPP1R9B) found in human tumors promotes the tumorigenic and stemness properties of cells. Theranostics. doi:10.7150/thno.53572 
  4. Santana-Molina, C, Rivas-Marin, E, Rojas, AM, & Devos, D.P. 2020. Origin and evolution of polycyclic triterpene synthesis. Molecular Biology and Evolution. Doi: 10.1093/molbev/msaa054 
  5. Martín-Doncel, E., Rojas, AM, Cantarero, L, & Lazo P.A., 2019 VRK1 functional insufficiency due to alterations in protein stability or kinase activity of human VRK1 pathogenic variants implicated in neuromotor syndromes. Scientific Reports. Doi: 10.1038/s41598-019-49821-7.
  6. Jiménez-Panizo, A., Pérez P., Rojas A., Fuentes-Prior, P., Estébanez-Perpiña, E. 2019. Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease. Endocrine Related Cancer. DOI: 10.1530/ERC-19-0132. 
  7. Andrés-León and Ana M. Rojas. 2019. miARma-Seq, a comprehensive pipeline for the simultaneous study and integration of miRNA and mRNA expression data. METHODS . DOI: 10.1016/j.ymeth.2018.09.002 
  8. Fuentes-Prior,P., Rojas, A., Hagler, AT., Estebanez-Perpina,E. (2018) Diversity of Quaternary structures regulates Nuclear receptor activities. Trends in Biochemical Sciences. DOI:10.1016/j.tibs.2018.09.005.
  9. Silva.J., Aivio, S., Knoble, PA., Casali, A., Vinaixa, M., Garcia-Cao, I., Coyaud, E., Jourdain, AA., Perez-Ferreros, P., Rojas, AM., Antolin-Fontes, A., Samino-Gene, S., Raught, B., Gozalez-Reyes, A., Ribas de Pouplana, L., Doherty, AJ., Yanes, O, and TH Stracker. (2018) EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. Nature Cell Biology. DOI:10.1038/s41556-017-0016-9.   
  10. Andres-Leon, E., Cases, I., Alonso,S.* and Rojas, A.M.*. (2017) Novel miRNA-mRNA interactions conserved in essential cancer pathways. Scientific Reports DOI:10.1038/srep46101.
  11. Castaneda-Garcia, A; Prieto, A.I., Rodriguez-Beltran, J., Alonso, N., Cantillon, D., Costas. C., Perez-Lago, L., Zegeye, E.D.., Herranz, M., Plocinski, P., Tonjum, T., Garcia de Viedma, D., Paget, M, Waddell, S.J., Rojas, A.M.*, Doherty, A.J.*, and Blazquez, J* (2017) A non-canonical mismatch repair pathway in prokaryotes. Nature communications DOI:10.1038/ncomms14246.
  12. Tristán-Clavijo E, G.-Scholl F, Macaya, A, Iglesias G, Rojas AM, Lucas, M, Castellano A, and Martinez-Mir, A. (2016) Dominant-negative mutation p.Arg324Thr in KCNA1 impairs Kv1.1 channel function in episodic ataxia. Movement disorders. DOI:10.1002/mds.26737.
  13.  Andres-Leon, E, Nuñez-Torres, R, and Ana M Rojas*. (2016) miARma-Seq: a comprehensive tool for miRNA, mRNA and circRNA analysis. Scientific Reports. DOI:10.1038/srep25749.
  14.  Basilico, F.*, Maffini, S*., Weir. J.R*., Prumbaum, D., Rojas, A.M, Zimniak, Z., De Antoni, A., Jeganathan, S., Voss, B., van Gerwen, S., Krenn, V., Massimiliano, L., Valencia, A., Vetter, I.R., Herzog, F., Raunser, S., Pasqualato, S and Musacchio, A. (2014) The pseudo GTPase CENP-M drives human kinetochore assembly. eLife. DOI: 10.7554/eLife.02978.
  15.  Rojas, A.M., Fuentes, G., Rausell, A., and Valencia, A. (2012). The Ras protein superfamily: Evolutionary tree and role of conserved amino acids. The Journal of Cell Biology. DOI:10.1083/jcb.201103008.