Grupos de investigación

Biología celular y Biotecnología

Gloria Brea Calvo
Bases moleculares de la deficiencia de Coenzima Q y bioenergética del desarrollo
Gloria Brea Calvo
Researcher associated to Dr Plácido Navas Lloret. UPO

» Resumen » Publicaciones Relevantes » Miembros del laboratorio y Colaboradores » back to research groups


Publicaciones Relevantes

  • Alcázar-Fabra M, Rodríguez-Sánchez F, Trevisson E, Brea-Calvo G. Primary Coenzyme Q deficiencies: A literature review and online platform of clinical features to uncover genotype-phenotype correlations. Free Radic Biol Med. 2021 Mar 4;167:141-180. doi: 10.1016/j.freeradbiomed.2021.02.046
  • Pérez-Pulido AJ, Asencio-Cortés G, Brokate-Llanos AM, Brea-Calvo G, Rodríguez-Griñolo R, Garzón A, Muñoz MJ. Serial co-expression analysis of host factors from SARS-CoV viruses highly converges with former high-throughput screenings and proposes key regulators. Briefings in Bioinformatics. 2021 Jan 18; bbbaa419. doi: 10.1093/bib/bbaa419
  • Luna-Sanchez M, Benincá C, Cerutti R, Brea-Calvo G, Yeates A, Scorrano L, Zeviani M, Viscomi C. Opa1 Overexpression Protects from Early-Onset Mpv17-/--Related Mouse Kidney Disease. Mol Ther. 2020 Aug 5;28 (8):1918-1930. doi: 10.1016/j.ymthe.2020.06.010.
  • Dhandapani PK, Begines-Moreno IM, Brea-Calvo G, Gärtner U, Graeber TG, Javier Sanchez G, Morty RE, Schönig K, Hoeve JT, Wietelmann A, Braun T, Jacobs HT, Szibor M. Hyperoxia but not AOX expression mitigates pathological cardiac remodeling in a mouse model of inflammatory cardiomyopathy. Sci Rep. 2019 Sep 4;9(1):12741. doi: 10.1038/s41598-019-49231-9.
  • Acosta Lopez, M.J., Trevisson, E., Canton, M., Vazquez-Fonseca, L., Morbidoni, V., Baschiera, E., Frasson, C., Pelosi, L., Rascalou, B., Desbats, M.A., et al. (2019). Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6. Oxid. Med. Cell. Longev.1–11.
  • Vázquez-Fonseca, L., Schaefer, J., Navas-enamorado, I., Matté, C., Ribes, A., Prieto-soler, S.Y., Dominguez-del-toro, E., Cabo, R. De, Jackson, S., and Navas, P. (2019). ADCK2 Haploinsufficiency Reduces Mitochondrial Lipid Oxidation and Causes Myopathy Associated with CoQ Deficiency. J. Clin. Med. 1–22.
  • Dhandapani, P.K., Begi, I.M., Brea-Calvo, G., Gärtner, U., Grae, T.G., Sanchez, G.J., Morty, R.E., Schönig, K., Hoeve, J., Wietelmann, A., et al. (2019). Hyperoxia but not AOX expression mitigates pathological cardiac remodeling in a mouse model of inflammatory cardiomyopathy. Scientific Reports.1–13.
  • Dogan SA, Cerutti R, Beninca C, Brea-Calvo G, Jacobs HT, Zeviani M, Szibor M, and Viscomi C (2018). Perturbed redox signalling exacerbates a mitochondrial myopathy. Cell Metabolism. DOI:https://doi.org/10.1016/j.cmet.2018.07.012
  • Alcázar-Fabra M, Trevisson E, Brea-Calvo G. (2018) Clinical syndromes associated with Coenzyme Q10 deficiency. Essays in Biochemistry., 62(3):377-398.
  • Yubero, D., Montero, R., Martín, M.A., Montoya, J., Ribes, A., Grazina, M., Trevisson, E., Rodriguez-Aguilera, J.C., Hargreaves, I.P., Salviati, L., Navas, P., Artuch, R.; CoQ deficiency study group (including Brea-Calvo, G). (2016) Secondary coenzyme Q10 deficiencies in oxidative phosphorylation (OXPHOS) and non-OXPHOS disorders. Mitochondrion, 30: 51-58.
  • Alcázar-Fabra M, Navas P, Brea-Calvo G. (2016) Coenzyme Q biosynthesis and its role in the respiratory chain structure. Biochimica et Biophysica Acta, 1857(8): 1073-1078.
  • Cascajo MV, Abdelmohsen K, Noh JH, Fernández-Ayala DJ, Willers IM, Brea G, López-Lluch G, Valenzuela-Villatoro M, Cuezva JM, Gorospe M, Siendones E, Navas P. (2016) RNA-binding proteins regulate cell respiration and coenzyme Q biosynthesis by post-transcriptional regulation of COQ7. RNA Biology, 13(7): 622-34.
  • Brea-Calvo G, Haack TB, Karall D, Ohtake A, Invernizzi F, Carrozzo R, Kremer L, Dusi S, Fauth C, Scholl-Bürgi S, Graf E, Ahting U, Resta N, Laforgia N, Verrigni D, Okazaki Y, Kohda M, Martinelli D, Freisinger P, Strom TM, Meitinger T, Lamperti C, Lacson A, Navas P, Mayr JA, Bertini E, Murayama K, Zeviani M, Prokisch H, Ghezzi D (2015) COQ4 Mutations Cause a Broad Spectrum of Mitochondrial Disorders Associated with CoQ10 Deficiency. American Journal of Human Genetics, 96(2): 309-317.
  • Brea-Calvo G, Siendones E, Sánchez-Alcázar JA & Navas P (2009). Cell survival from Chemotherapy depends on NF-kappaB transcriptional upregulation of Coenzyme Q biosynthesis. PLoSOne, 4(4): e5301.       
  • Artuch R, Brea-Calvo G, Briones P, Aracil A, Galvan M, Espinos C, Corral J, Volpini V, Ribes A, Andreu AL, Palau F, Sánchez-Alcázar JA, Navas P & Pineda M (2006). Cerebellar ataxia with coenzyme Q10 deficency: diagnosis and follow-up after coenzyme Q10 supplementation. J Neurol Sci, 246: 153-158.
  • Brea-Calvo G, Rodriguez-Hernandez A, Fernandez-Ayala DJM, Navas P & Sánchez-Alcázar JA (2006). Chemotherapy induces an increase in coenzyme Q10 levels in cancer cells lines. Free Radical Biology and Medicine, 40: 1293-1302.

More here: https://scholar.google.es/citations?hl=es&user=H-Lqgz4AAAAJ&view_op=list_works&sortby=pubdate