Grupos de investigación

Biología celular y Biotecnología

Regulación de la síntesis de coenzima Q y sus implicaciones en el alargamiento de la vida y el envejecimiento

Dr Carlos Santos Ocaña. UPO
Researcher associated to Dr Plácido Navas Lloret. UPO

» Resumen » Cinco publicaciones relevantes » Miembros del laboratorio y Colaboradores » back to research groups

Haucke, V., Santos-Ocaña, C., Hönliger, A., Tokatlidis, K., Pfanner, N., and Schatz, G. (1997) The bipartite targeting sequence directs the Mcr1 protein to two different submitochondrial compartments via a novel sorting pathway. Moll. Cell Biol. 17, 4024-4032.
Santos-Ocaña, C., Córdoba, F., Crane, F.L., Clarke, C.F., and Navas, P. (1998) Coenzyme Q6 and iron reduction are responsible for the extracellular ascorbate stabilization at the plasma membrane of Saccharomyces cerevisiae. J. Biol. Chem. 273, 8099-8105.
Santos-Ocaña, C., Do, T.Q., Padilla, S., Navas, P. and Clarke, C.F. (2002) Uptake of exogenous coenzyme Q and transport to mitochondria is required for bc1 complex stability in yeast Coq mutants J. Biol. Chem. 277, 10973-10981
Padilla, S., Jonassen, T., Jiménez-Hidalgo, M.A., Fernández-Ayala, D.J.M., Lopez-Lluch, G., Navas, P., Clarke C.F., and Santos-Ocaña, C. (2004) Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity. J. Biol. Chem. 279, 25995.