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Grupos de investigación

Regulación génica y morfogénesis

Javier Lopez-Rios
Desarrollo y evolución de vertebrados
Javier Lopez-Rios
Principal Investigator

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Publicaciones recientes más relevantes

  • Osterwalder M, Barozzi I, Tissières V, Fukuda-Yuzawa Y, Mannion BJ, Afzal SY, Lee EA, Zhu Y, Plajzer-Frick I, Pickle CS, Kato M, Garvin TH, Pham QT, Harrington AN, Akiyama JA, Afzal V, Lopez-Rios J, Dickel DE, Visel A, Pennacchio LA. (2018). Enhancer redundancy provides phenotypic robustness in mammalian development. Nature. 2018 Feb 8;554(7691):239-243.

  • Lopez-Rios J. (2016). The many lives of SHH in limb development and evolution. Semin Cell Dev Biol, 49:116-124.

  • Osterwalder M, Speziale S, Shoukry M, Mohan R, Ivanek R, Kohler M, Beisel C, Wen X, Scales SJ, Christoffels VM, Visel A, Lopez-Rios J* and Zeller R*. (2014). HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme. Dev Cell, 31:345 - 357.

  • Lopez-Rios J#, Duchesne A#, Speziale D, Andrey G, Peterson KA, German P, Ünal E, Liu J, Floriot S, Barbey S, Gallard Y, Müller-Gerbl M, Courtney AD, Klopp C, Rodriguez S, Ivanek R, Beisel C, Wicking C, Iber D, Robert B, McMahon AP, Duboule D and Zeller R. (2014) Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs. Nature, 511(7507):46-51.

  • Lopez-Rios J, Speziale D, Robay D, Scotti M, Osterwalder M, Nusspaumer G, Galli A, Holländer GA, Kmita M, Zeller R. (2012). GLI3 Constrains Digit Number by Controlling Both Progenitor Proliferation and BMP-Dependent Exit to Chondrogenesis. Dev Cell, 22:837–848.

  • Osterwalder M, Galli A, Rosen B, Skarnes WC, Zeller R*, Lopez-Rios J*. (2010). Dual RMCE for efficient re-engineering of mouse mutant alleles. Nat Methods, 7: 893-895.

    #autores con igual contribución; *autores para correspondencia