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Universidad Pablo de Olavide Junta de Andalucía Consejo Superior de Investigaciones Científicas

Research groups

Cell biology and Biotechnology

Dr Manuel Ballesteros. UPO
Ubiquinone Biosynthesis: Metabolic regulation and integration in the cellular oxidative stress response
Dr Manuel Ballesteros. UPO
Researcher associated to Dr Plácido Navas Lloret. UPO

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Five relevant publications

  • Fredriksson, Å., Ballesteros, M., Peterson C.N., Persson O., Silhavy T.J. and Nyström, T. (2007) Decline in ribosomal fidelity contributes to the accumulation and stabilization of the master stress response regulator sigmaS upon carbon starvation. Genes Dev 21: 862-874.
  • Fredriksson, Å., Ballesteros, M., Dukan S. and Nyström, T. (2006) Induction of the heat shock regulon in response to increased mistranslation requires oxidative modification of the malformed proteins. Mol. Microbiol. 59(1): 350-359.
  • Fredriksson, Å., Ballesteros, M., Dukan S. and Nyström, T. (2005) Defence against protein carbonylation by DnaK/DnaJ and proteases of the heat shock regulon J. Bacteriol. 187(12):4207-13
  • Ballesteros, M., Fredricksson, Å., Henriksson, J. and Nyström, T. (2001) Bacterial senescence: protein oxidation in non-proliferating cells is dictated by the accuracy of the ribosomes. EMBO J., 20 (18): 5280-5289.
  • Dukan, S., Farewell, A., Ballesteros, M., Taddei, F., Radman, M., and Nystrom T. (2000) Protein oxidation in response to increased transcriptional or translational errors. Proc. Natl. Acad. Sci. U S A., 97(11):5746-9.