Research groups

Cell biology and Biotechnology

Programmed cell death during development and disease

Dr Jose Antonio Sánchez-Alcazar. UPO
Principal Investigator

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Five relevant publications

José A. Sánchez-Alcázar, Ángeles Rodríguez-Hernández, Mario Cordero, Daniel J. M. Fernández-Ayala, Gloria Brea-Calvo, Katherina Garcia, and Plácido Navas (2007). The Apoptotic Microtubule Network preserves plasma membrane integrity during the execution phase of apoptosis. Apoptosis 12(7):1195-208.

Ángeles Rodríguez-Hernández, Mario D. Cordero, Leonardo Salviati, Rafael Artuch, Mercé Pineda, Paz Briones, Lourdes Gómez Izquierdo, David Cotán, Plácido Navas, and José A. Sánchez-Alcázar (2009). Coenzyme Q deficiency triggers mitochondria degradation by mitophagy. Autophagy 5(1): 19-32.

Manuel Oropesa, Mario de la Mata, Juan Garrido Maraver, Mario D. Cordero, David Cotán, Ángeles Rodríguez-Hernández, Irene Domínguez-Moñino, Manuel de Miguel, Plácido Navas and José A. Sánchez-Alcázar. Apoptotic microtubule network organization and maintenance depend on high cellular ATP levels and energized mitochondria. Apoptosis, 2011 in press.

Mario D. Cordero; Elísabet Alcocer-Gómez; Manuel de Miguel; Francisco Javier Cano-García; Carlos M. Luque; Patricia Fernández-Riejo; Ana María Moreno Fernández; José Antonio Sánchez-Alcazar. Coenzyme Q10: a novel therapeutic approach for Fibromyalgia? Case series with 5 patients. Mitochondrion, 2011 in press

David Cotán, Mario D. Cordero, Juan Garrido-Maraver, Manuel Oropesa-Ávila, Ángeles Rodríguez-Hernández, Lourdes Gómez Izquierdo, Mario De la Mata, Manuel De Miguel, Juan Bautista Lorite, Eloy Rivas Infante, Sandra Jackson, Plácido Navas, and José A. Sánchez-Alcázar. Secondary coenzyme Q10 deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts. FASEB J, 2011, in press.