Research groups

Cell biology and Biotechnology

Chemotherapy- induced apoptosis

Dr Jose Antonio Sánchez-Alcazar. UPO
Researcher associated to Dr Plácido Navas Lloret. UPO

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Five relevant publications

J. A. Sanchez-Alcazar, J.G. Ault, A. Khodjakov, and E. Schneider. Increasded Mitochondrial Cytochrome c Levels and Mitochondrial Hyperpolarization Precede Camptothecin-Induced Apoptosis in Jurkat Cells (2000). Cell Death and Differentiation 7 (11), 1090-1100.

J. A. Sanchez-Alcazar, A. Khodjakov, J.G. Aula, and E. Schneider (2001). Anticancer drugs induce increased mitochondrial cytochrome c expression that precedes cell death. Cancer Research 61, 1038-1044.

G. Brea-Calvo, A. Rodríguez-Hernández, D. J. M. Fernández-Ayala, P. Navas, and J. A. Sánchez-Alcázar (2006). Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines. Free Radical Biology & Medicine 40, 1293-1302.

José A. Sánchez-Alcázar, Ángeles Rodríguez-Hernández, Mario Cordero, Daniel J. M. Fernández-Ayala, Gloria Brea-Calvo, Katherina Garcia, and Plácido Navas (2007). The Apoptotic Microtubule Network preserves plasma membrane integrity during the execution phase of apoptosis. Apoptosis 12(7):1195-208.

Ángeles Rodríguez-Hernández, Mario D. Cordero, Leonardo Salviati, Rafael Artuch, Mercé Pineda, Paz Briones, Lourdes Gómez Izquierdo, David Cotán, Plácido Navas, and José A. Sánchez-Alcázar (2009). Coenzyme Q deficiency triggers mitochondria degradation by mitophagy. Autophagy 5(1): 19-32.