Research groups
Cell biology and Biotechnology
Principal Investigator
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Relevant publications
1. Fierro-González JC, González-Barrios M, Miranda-Vizuete A*, Swoboda P. (2011) The thioredoxin TRX-1 regulates adult lifespan extension induced by dietary restriction in Caenorhabditis elegans. Biochem Biophys Res Commun. 406: 478-82.
2. Fierro-González JC, Cornils A, Alcedo J, Miranda-Vizuete A*, Swoboda P. (2011) The thioredoxin TRX-1 modulates the function of the insulin-like neuropeptide DAF-28 during dauer formation in Caenorhabditis elegans. PLoS One. 6: e16561.
3. Stenvall J, Fierro-González JC, Swoboda P, Saamarthy K, Cheng Q, Cacho-Valadez B, Arnér ES, Persson OP, Miranda-Vizuete A, Tuck S. (2011) Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 108: 1064-9.
4. Calvo AC, Pey AL, Miranda-Vizuete A, Døskeland AP, Martinez A. (2011) Divergence in enzyme regulation between Caenorhabditis elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine. Biochem J. 434: 133-41.
5. Morgan KL, Estevez AO, Mueller CL, Cacho-Valadez B, Miranda-Vizuete A, Szewczyk NJ, Estevez M. (2010) The glutaredoxin GLRX-21 functions to prevent selenium-induced oxidative stress in Caenorhabditis elegans. Toxicol Sci. 118: 530-43.
6. Miranda-Vizuete A, Fierro González JC, Gahmon G, Burghoorn J, Navas P, Swoboda P. (2006) Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX-1, a thioredoxin expressed in ASJ sensory neurons. FEBS Lett. 580: 484-90.
* Equally contributed as senior author and author for correspondence