Research groups

Cell biology and Biotechnology

Coenzyme Q synthesis in Saccharomyces cerevisae and its implications in lifespan and ageing

Dr Carlos Santos Ocaña. UPO
Researcher associated to Dr Plácido Navas Lloret. UPO

» Summary » Five relevant publications » Lab members & Collaborators » back to research groups

Haucke, V., Santos-Ocaña, C., Hönliger, A., Tokatlidis, K., Pfanner, N., and Schatz, G. (1997) The bipartite targeting sequence directs the Mcr1 protein to two different submitochondrial compartments via a novel sorting pathway. Moll. Cell Biol. 17, 4024-4032.
Santos-Ocaña, C., Córdoba, F., Crane, F.L., Clarke, C.F., and Navas, P. (1998) Coenzyme Q6 and iron reduction are responsible for the extracellular ascorbate stabilization at the plasma membrane of Saccharomyces cerevisiae. J. Biol. Chem. 273, 8099-8105.
Santos-Ocaña, C., Do, T.Q., Padilla, S., Navas, P. and Clarke, C.F. (2002) Uptake of exogenous coenzyme Q and transport to mitochondria is required for bc1 complex stability in yeast Coq mutants J. Biol. Chem. 277, 10973-10981
Arroyo, A, Modriansky M, Serinkan FB, Bello RI, Matsura T, Jiang J, Tyurin VA, Tyurina YY, Fadeel B, Kagan VE. (2002) NADPH oxidase-dependent oxidation and externalization of phosphatidylserine during apoptosis in Me2SO-differentiated HL-60 cells. Role in phagocytic clearance. J Biol Chem. 277, 49965-75.
Padilla, S., Jonassen, T., Jiménez-Hidalgo, M.A., Fernández-Ayala, D.J.M., Lopez-Lluch, G., Navas, P., Clarke C.F., and Santos-Ocaña, C. (2004) Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity. J. Biol. Chem. 279, 25995.