Research groups

Gene regulation and morphogenesis

Dr Maria Dolores (Lola) Martín Bermudo. CSIC
Genetic and molecular mechanisms regulating cell migration and invasion
Dr Maria Dolores (Lola) Martín Bermudo. CSIC
Principal Investigator

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Five relevant publications

Malartre, M., Derya, A., Fernández-Amador, F. and Martín-Bermudo, M. D. (2010) The guanine exchange factor vav controls axon growth and guidance during Drosophila development. J Neuroscience, 30:2257-2267.

Cobreros  Reguera, L, Fernández-Miñán, A., Fernández-Espartero, C.H., López-Schier, H., González-Reyes, A* and Martín-Bermudo, M.D. * (2010) The Ste-20 like kinase misshapen regulates the invasive behaviour of ovarian epithelial cells in Drosophila. (*Co-corresponding authors). EMBO Reports, 11:943-949.

J.M. Urbano, Domínguez Jiménez, P., Estrada, B. and M.D. Martín-Bermudo (2011) PS integrins and Laminins: Key Regulators of cell migration during Drosophila embryogenesis. PLoS One 6 (9); e23893.

C. H. Fernández-Espartero, D. Ramel, M. Farago, M. Malartre, C. M Luque, S. Limanovich, S. Katzav, G. Emery and Martín-Bermudo, M. D. (2013). The GEF Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation. J. Cell Science, 126:2285-2293.

K. Comber, S. Huelsmann, I. Evans, B. J. Sánchez-Sánchez, A. Chalmers, R. Reuter, W. Wood and M. D. Martín-Bermudo (2013) A dual role for the βPS integrin myospheroid in mediating Drosophila embryonic macrophage migration. J. Cell Science, 126: 3475-3484.

Pérez Moreno, J., Bischoff, M., M. D. Martín-Bermudo, and Estrada, B. (2014) The transmembrane proteoglycan Perdido is essential for in vivo myofibrillogenesis and proper sarcomeric structure. J. Cell Science, 127: 3162-3173.

Gómez-Lamarca, M.J., Cobreros  Reguera, L., Ibáñez-Jiménez, B.,Palacios, I.M. and M. D. Martín-Bermudo (2014) Integrins regulate epithelial cell differentiation by modulating Notch activity.  J. Cell Science, 127: 4667-4678.

Martín-Bermudo, M. D., Pierre-Luc Bardet, Yohanns Bellaicheand and Malartre, M. (2015) The Vav oncogene antagonizes EGFR signaling and regulates adherens junction dynamics during Drosophila eye development. Development, 142: 1492-1501.