.

Research groups

Gene regulation and morphogenesis

Javier Lopez-Rios
Vertebrate development and evolution
Javier Lopez-Rios
Principal Investigator

» Summary » Relevant publications » Lab members & Collaborators » back to research groups


Relevant publications

  • Osterwalder M, Barozzi I, Tissières V, Fukuda-Yuzawa Y, Mannion BJ, Afzal SY, Lee EA, Zhu Y, Plajzer-Frick I, Pickle CS, Kato M, Garvin TH, Pham QT, Harrington AN, Akiyama JA, Afzal V, Lopez-Rios J, Dickel DE, Visel A, Pennacchio LA. (2018). Enhancer redundancy provides phenotypic robustness in mammalian development. Nature. 2018 Feb 8;554(7691):239-243.
  • Lopez-Rios J. (2016). The many lives of SHH in limb development and evolution. Semin Cell Dev Biol, 49:116-124.
  • Lopez-Rios J#, Duchesne A#, Speziale D, Andrey G, Peterson KA, German P, Ünal E, Liu J, Floriot S, Barbey S, Gallard Y, Müller-Gerbl M, Courtney AD, Klopp C, Rodriguez S, Ivanek R, Beisel C, Wicking C, Iber D, Robert B, McMahon AP, Duboule D and Zeller R. (2014) Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs. Nature, 511(7507):46-51.
  • Osterwalder M, Speziale S, Shoukry M, Mohan R, Ivanek R, Kohler M, Beisel C, Wen X, Scales SJ, Christoffels VM, Visel A, Lopez-Rios J* and Zeller R*. (2014). HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme. Dev Cell, 31:345 - 357.
  • Lopez-Rios J, Speziale D, Robay D, Scotti M, Osterwalder M, Nusspaumer G, Galli A, Holländer GA, Kmita M, Zeller R. (2012). GLI3 Constrains Digit Number by Controlling Both Progenitor Proliferation and BMP-Dependent Exit to Chondrogenesis. Dev Cell, 22:837–848.
  • Osterwalder M, Galli A, Rosen B, Skarnes WC, Zeller R*, Lopez-Rios J*. (2010). Dual RMCE for efficient re-engineering of mouse mutant alleles. Nat Methods, 7: 893-895.

    #equal contribution authors; *co-corresponding authors