Research groups

Gene regulation and morphogenesis

Cell integration of diverse genetic inputs during the morphogenesis of complex organs

Dr James Castelli-Gair Hombría. CSIC
Principal Investigator

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Denholm B, Brown S., Ray R., Ruiz-Gómez M., Skaer H. and Castelli-Gair Hombría J. (2005). crossveinless-c is a RhoGAP required for actin reorganisation during morphogenesis. Development 132, 2389-2400.
Lovegrove B., Simões S., Rivas M.L., Sotillos S., Johnson K., Knust E., Jacinto A., Castelli-Gair Hombría J. (2006) Co-ordinated control of cell adhesion, cell polarity and cytoskeleton underlies Hox induced organogenesis in Drosophila. Current Biology 16, 2206-2216.
Sotillos S., Díaz-Meco, M.T., Moscat, J. and Castelli-Gair Hombría J. (2008). Polarized subcellular localization of JAK/STAT components is required for efficient signalling. Current Biology. 18, 624-629.
Rivas M.L., Cobreros L., Zeidler M. P., and Castelli-Gair Hombría J. (2008). Plasticity of Drosophila STAT DNA binding shows an evolutionary basis for STAT transcription factor preferences. EMBOreports 9, 1114-1120.
Sotillos, S., Espinosa-Vázquez J.M., Foglia F., Hu N. and Castelli-Gair Hombría J. (2010). An efficient approach to isolate STAT regulated enhancers uncovers STAT92E fundamental role in Drosophila tracheal development. Developmental Biology 340, 571-592.